Exploring causal relationship between 41 inflammatory cytokines and marginal zone lymphoma: A bidirectional Mendelian randomization study
MIG, IL-10, B-NGF, and IFN-γ are potential biomarkers and therapeutic targets for MZL. IFN-γ likely acts as a downstream molecule in MZL pathogenesis, offering novel insights into MZL-related research, clinical diagnosis, and treatment strategies.
Authors
- Huali Hu (ORCID: https://orcid.org/0009-0003-4697-0467)
- Xinhang Hu
- Huang Xing-chun
- Wangcheng Zhao
- Yifan Ouyang (ORCID: https://orcid.org/0009-0000-6371-2281)
- Muyun Peng (ORCID: https://orcid.org/0000-0002-8346-7479)
- Fenglei Yu (ORCID: https://orcid.org/0000-0003-3409-065X)
- Zhi Yang (ORCID: https://orcid.org/0000-0002-0871-5882)
- Wang Li (ORCID: https://orcid.org/0000-0002-7207-3837)
- Zhe Zhang (ORCID: https://orcid.org/0009-0004-9608-6626)
- Xuyang Yi
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Open Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1515/med-2025-1171
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China