Outpatient Management of Bispecific Related Toxicities: An Observational Study of Safety Outcomes and Resource Utilization
An outpatient-based practice for BsAb administration demonstrated safety and cost savings. The description of our practice and results of this study provide valuable insights into the safety, feasibility, and resource stewardship of outpatient management of BsAbs. Future research should attempt to predict and stratify CRS risk to deliver a tailored supportive strategy and continued increase of outpatient management.
Authors
- David Dingli (ORCID: https://orcid.org/0000-0001-7477-3004)
- Jenna R. Puttkammer (ORCID: https://orcid.org/0000-0002-2735-5608)
- Morie A. Gertz (ORCID: https://orcid.org/0000-0002-3853-5196)
- Adrienne N. Nedved (ORCID: https://orcid.org/0009-0005-5667-4543)
- Shaji Kunnathu Kumar (ORCID: https://orcid.org/0000-0001-5392-9284)
- Prashant Kapoor (ORCID: https://orcid.org/0000-0002-4342-364X)
- Moritz Binder (ORCID: https://orcid.org/0000-0001-9014-9658)
- Jason N. Barreto (ORCID: https://orcid.org/0000-0003-2146-5766)
- Chelsee Jensen (ORCID: https://orcid.org/0000-0003-1954-4414)
- Tyler B. Sandahl (ORCID: https://orcid.org/0009-0009-5736-2460)
- Lucy Holmes (ORCID: https://orcid.org/0000-0001-6680-0594)
- Kristin Cole (ORCID: https://orcid.org/0000-0002-8783-0191)
- Rahma Warsame (ORCID: https://orcid.org/0000-0003-0240-0326)
- Joselle Cook (ORCID: https://orcid.org/0000-0001-5335-9533)
- Wilson I. Gonsalves (ORCID: https://orcid.org/0000-0001-6890-969X)
- Taxiarchis Kourelis (ORCID: https://orcid.org/0000-0001-8573-9434)
- Yi Lin (ORCID: https://orcid.org/0000-0002-1556-6416)
- Suzanne R. Hayman (ORCID: https://orcid.org/0000-0001-9422-2621)
- A. Kosobud
- Justine L. Wilson-Miller
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- JCO Oncology Practice
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1200/op-24-00930
- Citations
- 2
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 2.09