The brain’s internal echo: Longer timescales, stronger recurrent connections and higher neural excitation in self regions

Our findings demonstrate the intrinsic nature of the distinction of self and non-self regions within the brain's global uni-transmodal topography as well as their underlying physiological differences with higher levels in both recurrent connections and neural excitation in self regions. The increased recurrent connections in self regions, together with their higher levels of neural excitation and the longer autocorrelation window, may be ideally suited to mediate their self-referential processing: this can thus be seen as a form of 'psychological recurrence' where one and the same input/stimulus is processed in a prolonged echo-chamber like way, that is, an internal echo within the self regions themselves.