Effectiveness of Frequently Used TNF Inhibitors vs. Conventional Immunosuppressive Therapies for Noninfectious Uveitis
Our results suggest COMB is more effective than CONV at achieving disease quiescence and corticosteroid sparing success among patients with active noninfectious uveitis. More research is needed to determine if TNFi alone is superior to CONV for uveitic corticosteroid-sparing.
Authors
- John H. Kempen (ORCID: https://orcid.org/0000-0002-2967-4792)
- Janet L. Davis (ORCID: https://orcid.org/0000-0001-6395-5881)
- Sen Hou (ORCID: https://orcid.org/0000-0002-6871-4419)
- Sunir J. Garg (ORCID: https://orcid.org/0000-0002-9115-6080)
- Paul Latkany
- Teresa L. Liesegang
- Eric B. Suhler (ORCID: https://orcid.org/0000-0003-3674-037X)
- Russell W. Read (ORCID: https://orcid.org/0000-0003-4985-8908)
- Sapna S. Gangaputra (ORCID: https://orcid.org/0000-0001-5461-8568)
- Kurt Dreger
- Debra A. Goldstein
- Srishti Kothari (ORCID: https://orcid.org/0000-0002-3065-4975)
- Careen Y. Lowder (ORCID: https://orcid.org/0000-0001-6723-7238)
- Jeanine M. Buchanich (ORCID: https://orcid.org/0000-0003-4658-3654)
- C. Stephen Foster (ORCID: https://orcid.org/0000-0002-6612-5653)
- Pichaporn Artornsombudh (ORCID: https://orcid.org/0000-0001-8451-5623)
- Gui‐Shuang Ying (ORCID: https://orcid.org/0000-0002-5752-1355)
- Douglas A. Jabs (ORCID: https://orcid.org/0000-0002-0368-1361)
- Glenn J. Jaffe (ORCID: https://orcid.org/0000-0003-2568-7892)
- Nisha R. Acharya (ORCID: https://orcid.org/0000-0002-9762-9475)
- Grace A. Levy-Clarke (ORCID: https://orcid.org/0000-0001-8801-7736)
- J. T. Rosenbaum
- Nirali Bhatt
- Craig Newcomb
- Jennifer E. Thorne (ORCID: https://orcid.org/0009-0004-0711-6134)
- Gary N. Holland
- Tonetta D. Fitzgerald
- Yannek I. Liederman
- for the Systemic Immunosuppressive Therapy for Eye Diseases
Institutions
- Northwestern University (US)
- West Virginia University (US)
- Portland State University (US)
- Massachusetts Eye and Ear Infirmary (US)
- National Institutes of Health (US)
- Cleveland Clinic (US)
- Harvard University (US)
- Johns Hopkins University (US)
- University of Miami (US)
- Chulalongkorn University (TH)
- Legacy Health (US)
- Oregon Health & Science University (US)
- University of Pittsburgh (US)
- Duke University (US)
- University of California, San Francisco (US)
- New York Eye and Ear Infirmary (US)
- Johns Hopkins Medicine (US)
- Veterans Health Administration (US)
- Royal Navy (GB)
- University of Alabama at Birmingham (US)
- Doheny Eye Institute (US)
- Massachusetts Eye Research and Surgery Institute (US)
- Cleveland Eye Clinic (US)
- Addis Ababa University (ET)
- University of Pennsylvania (US)
- Wills Eye Hospital (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Ocular Immunology and Inflammation
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1080/09273948.2025.2479802
- Citations
- 1
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Research to Prevent Blindness
- National Institutes of Health
- National Eye Institute