Association of time-to-treatment with prognosis in pneumocystis pneumonia among immunocompromised patients without HIV infection: a multi-center, retrospective observational cohort study
This study emphasizes the importance of accurate diagnosis and tailored management based on disease severity rather than immediate empirical treatment, as early treatment initiation was not significantly associated with 30-day or 180-day mortality in non-HIV PCP.
Authors
- Kei Nakashima (ORCID: https://orcid.org/0000-0001-6080-1801)
- Haruka Fujioka (ORCID: https://orcid.org/0009-0003-9192-3870)
- Ayumu Otsuki (ORCID: https://orcid.org/0000-0001-9093-3442)
- Hiroyuki Ito (ORCID: https://orcid.org/0000-0001-7398-8943)
- Daisuke Shichi
- Yuya Homma
- Yoshihito Otsuka (ORCID: https://orcid.org/0009-0000-2671-7585)
- Shin‐ichiro Ohmura (ORCID: https://orcid.org/0000-0001-8651-4149)
- Tomohisa Watari (ORCID: https://orcid.org/0000-0001-5507-8356)
- Toshiaki Miyamoto (ORCID: https://orcid.org/0000-0002-1944-4280)
- Tatsuya Nagai (ORCID: https://orcid.org/0000-0002-6203-8448)
- Hiroki Matsui (ORCID: https://orcid.org/0000-0002-1049-7925)
Institutions
- Seirei Mikatabara General Hospital (JP)
- Kameda Medical Center (JP)
- University of Tokyo Health Sciences (JP)
- Seirei Hamamatsu General Hospital (JP)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s12879-025-10933-3
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00