Modulation of Functional Activity of <i>INS-VNTR</i> Class I Haplotype Derived from Patients With Type 1 Diabetes
Longer TRUs of the class I INS-VNTR haplotype favors INS expression in thymus and tolerance induction. Vitamin A supplementation could be beneficial for prevention of insulin autoimmunity at the early stages of T1D onset.
Authors
- Chiachen Chen
- Liping Yu (ORCID: https://orcid.org/0000-0003-0664-2154)
- Michael S. Lan (ORCID: https://orcid.org/0000-0003-4596-5677)
Institutions
- Louisiana State University Health Sciences Center New Orleans (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1210/clinem/dgaf243
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00