Urine Metabolites as Indicators of Chronic Pain and Related Symptoms in Active-Duty Service Members: A Secondary Data Analysis of a Pragmatic Clinical Trial With SMART Design
Our finding of associations between the UMPI and components of the self-reported measures supports the development of the UMPI and these four urine metabolites as biomarkers for chronic pain outcomes. Further research is planned and will be essential for establishing mechanistic insight and guiding biomarker development within the context of pain management.
Authors
- Hannah Choi (ORCID: https://orcid.org/0000-0002-1278-7969)
- Nicholas M. Ieronimakis (ORCID: https://orcid.org/0000-0002-7078-8230)
- Ardith Z. Doorenbos (ORCID: https://orcid.org/0000-0002-3899-8238)
- Honor McQuinn (ORCID: https://orcid.org/0000-0002-2018-6784)
- Tyler J. Snow (ORCID: https://orcid.org/0000-0003-3255-5580)
- Diane M. Flynn
- Jeffrey C Ransom (ORCID: https://orcid.org/0000-0001-6510-8352)
- Nathan Tintle (ORCID: https://orcid.org/0000-0003-1447-9107)
- Dahee Wi (ORCID: https://orcid.org/0000-0002-8951-2816)
- Kira P. Orr
Institutions
- Twitter (United States) (US)
- Madigan Army Medical Center (US)
- Illinois College (US)
- University of Washington (US)
- University of Illinois Chicago (US)
- The Geneva Foundation (US)
- Statistical Research (United States) (US)
Publication Details
- Journal
- Nursing Research
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1097/nnr.0000000000000827
- Citations
- 2
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.16