Impaired sensitivity to thyroid hormones is associated with increased body fat mass/muscle mass ratio (F/M) in the euthyroid population
Impaired central, but not peripheral sensitivity to thyroid hormones was associated with increased body fat mass/muscle mass ratio (F/M), this association was obvious in males, individuals with age < 65 years and BMI ≥ 25 kg/m<sup>2</sup>, with different inflection points. Maybe F/M independently affects thyroid hormone sensitivity, we need more clinical and basic studies in the future.
Authors
- Guojuan Wang
- Qianqian Zhang (ORCID: https://orcid.org/0000-0003-3002-644X)
- Qiange Ye (ORCID: https://orcid.org/0009-0006-6892-0884)
- Yue Wang (ORCID: https://orcid.org/0000-0002-1211-2822)
- Li Chen (ORCID: https://orcid.org/0000-0002-9478-6432)
- Wei Liu (ORCID: https://orcid.org/0000-0003-2822-7058)
- Ying Li (ORCID: https://orcid.org/0000-0002-9205-7981)
- Yan Liu (ORCID: https://orcid.org/0009-0003-3120-3011)
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Hefei First People's Hospital (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s13098-025-01693-w
- Citations
- 3
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.88
Funders
- National Natural Science Foundation of China