Vitamin D and Alopecia Areata: From Mechanism to Therapeutic Implications
(1) Vitamin D serves as a critical immunomodulator in AA, regulating follicular immune privilege and key inflammatory pathways involved in disease pathogenesis. (2) Vitamin D deficiency is frequently observed in patients with AA and has been associated with increased disease severity, prolonged duration, and a higher risk of relapse. (3) Emerging evidence supports the therapeutic potential of vitamin D analogs and supplementation in AA, positioning vitamin D as a promising adjunct or primary treatment modality.
Authors
- Luis Enrique Cano‐Aguilar (ORCID: https://orcid.org/0000-0003-0710-5430)
- Erick Alejandro Jiménez-Herrera (ORCID: https://orcid.org/0000-0002-0606-7113)
- Eduardo Corona‐Rodarte (ORCID: https://orcid.org/0000-0002-9807-0546)
- Carlos A. Barrera‐Ochoa (ORCID: https://orcid.org/0000-0003-4480-4388)
- Daniel Asz‐Sigall (ORCID: https://orcid.org/0000-0003-1848-5686)
- Bianca Eunice López-Zenteno
- Ricardo Parra-Guerra
- Rafael Zubirán
Institutions
- National Institutes of Health (US)
- Mexican Social Security Institute (MX)
- Secretaría de Salud de Jalisco (MX)
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- National Heart, Lung, and Blood Institute (US)
- Hospital General Dr. Manuel Gea Gonzalez (MX)
- Centro Médico ABC (MX)
Publication Details
- Journal
- Skin Appendage Disorders
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1159/000545711
- Citations
- 3
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.51
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute