Mental distress and inflammation in bladder cancer: The nerve makes things less vague
Our findings suggest that high vagal activity, as indicated by higher HRV, may mitigate the adverse effects of psychological distress on immune-inflammatory responses in patients with bladder cancer. Stress-related inflammation took place under conditions of low HRV, highlighting the potential role of autonomic regulation in cancer prognosis. Future research should further explore these relationships to develop interventions aimed at improving patient outcomes through stress management and enhanced vagal nerve activity to regulate inflammation in cancer.
Authors
- Mária Bucová (ORCID: https://orcid.org/0000-0003-4742-3505)
- Ľuba Hunáková (ORCID: https://orcid.org/0000-0003-2159-0807)
- Yori Gidron
- Magda Suchánková (ORCID: https://orcid.org/0000-0002-5516-9845)
- Vladimı́ra Ďurmanová (ORCID: https://orcid.org/0000-0001-7422-0194)
- Iveta Mikolášková (ORCID: https://orcid.org/0000-0003-4443-9069)
Institutions
- Comenius University Bratislava (SK)
- University of Haifa (IL)
Publication Details
- Journal
- Brain Behavior & Immunity - Health
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.bbih.2025.100995
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00