TTC4 Overexpression Attenuates Allergic Rhinitis via Inhibiting AMPK-Mediated Autophagy
TTC4 overexpression attenuated allergic symptoms and inflammation via rebalancing Th1/Th2 percentage and inhibiting autophagy of nasal mucosal epithelial cells through inhibition of the production of IL-33. Our experiments may provide novel idea for the treatment of AR.
Authors
- Yinping Huo (ORCID: https://orcid.org/0000-0001-6937-0964)
- Chaofeng Liu (ORCID: https://orcid.org/0000-0003-2942-1418)
- Yunliang Liu
- Shanshan Li (ORCID: https://orcid.org/0009-0003-1022-4665)
- Zhihui Liu (ORCID: https://orcid.org/0000-0001-8650-9104)
- Xiaoyan Wang (ORCID: https://orcid.org/0000-0002-2980-047X)
- Yang� Yang (ORCID: https://orcid.org/0000-0003-1222-1209)
- Zhu Mao
Institutions
- Fujian Medical University (CN)
- Fuzhou Maternity and Child Health Care Hospital (CN)
- Fujian Provincial Hospital (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1159/000545439
- Citations
- 2
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 1.59