Improving Bioplastic Production: Enhanced P(3HB-<i>co</i>-3HHx) Synthesis from Glucose by Using Mutant <i>Cupriavidus necator</i>.
Our study reveals the potential of newly engineered <i>C. necator</i> NSDG-GGΔB1/pBPP-ccr<sub>Me</sub>J<sub>Ac</sub>-emd mutant strain for efficient PHBHHx copolymer production. Process parameters such as glucose and urea concentration, and agitation rate significantly influenced PHBHHx yield. This research stands out by utilizing a novel strain for PHBHHx synthesis. Characterization confirmed high-quality polymer production. Our findings offer a sustainable approach for converting inexpensive carbon sources into valuable PHBHHx though further optimization for scale-up is warranted.
Authors
- Kumar Sudesh (ORCID: https://orcid.org/0000-0003-4756-9192)
- Toshiaki Fukui (ORCID: https://orcid.org/0000-0003-4557-6284)
- Peyman Abdeshahian
- Nazila Biglari (ORCID: https://orcid.org/0000-0002-9270-3402)
- Izumi Orita (ORCID: https://orcid.org/0000-0002-9232-6221)
Institutions
- Tokyo Institute of Technology (JP)
- Universiti Sains Malaysia (MY)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-01
- DOI
- https://doi.org/10.30498/ijb.2024.445254.3884
- Primary Topic
- biodegradable polymer synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan International Cooperation Agency
- Japan Science and Technology Agency
- Science and Technology Research Partnership for Sustainable Development