Functional coupling between chronic pain and the autonomic nervous system revealed by neuromodulation techniques. Comment on ‘Effect of neuromodulation for chronic pain on the autonomic nervous system: a systematic review’ (BJA Open 2024; 11: 100305)
We read with interest the article published by Billet and colleagues1 on the effects of neuromodulation therapy for pain concomitantly produced on autonomic nervous system (ANS) parameters. This systematic review showed heterogeneous effects of different types of neuromodulation techniques on various ANS tests. The authors especially highlighted a possible decrease in sympathetic activity produced by dorsal root ganglion stimulation, an approach currently proposed for the treatment of complex regional pain syndromes (CRPS),2 which is a typical example of the pathophysiological interactions between pain and ANS.
Authors
- Jean‐Pascal Lefaucheur (ORCID: https://orcid.org/0000-0002-0294-8239)
- Chantal Delon‐Martin (ORCID: https://orcid.org/0000-0003-0766-0346)
- Hasan Hodaj
Institutions
- Inserm (FR)
- Université Paris-Est Créteil (FR)
- Centre Hospitalier Universitaire de Grenoble (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Grenoble Institute of Neurosciences (FR)
- Université Grenoble Alpes (FR)
Publication Details
- Journal
- BJA Open
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.bjao.2025.100393
- Citations
- 1
- Primary Topic
- Pain Management and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.19