Collider Bias Is an Insufficient Explanation for the Inverse Obesity Paradox in Prostate Cancer

Collider bias alone is unlikely to explain the inverse obesity paradox in (localized) PCa, reinforcing some mechanistic evidence that the observed positive relationship between BMI and PCa death is real, and not a statistical artifact. This finding emphasizes the importance of exploring alternative mechanisms beyond collider bias to better understand the underlying factors driving this paradox.

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Publication Details

Journal
Cancer Medicine
Published
2025-04-01
DOI
https://doi.org/10.1002/cam4.70871
Primary Topic
Statistical Methods and Inference
Type
article
Field-Weighted Citation Impact
0.00

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article

Collider Bias Is an Insufficient Explanation for the Inverse Obesity Paradox in Prostate Cancer

Tanja Stocks, Josef Fritz, Christel Häggström
1 links
Cancer Medicine
Statistical Methods and Inference
article

Collider Bias Is an Insufficient Explanation for the Inverse Obesity Paradox in Prostate Cancer

Tanja Stocks, Josef Fritz, Christel Häggström
article en

Abstract

Collider bias alone is unlikely to explain the inverse obesity paradox in (localized) PCa, reinforcing some mechanistic evidence that the observed positive relationship between BMI and PCa death is real, and not a statistical artifact. This finding emphasizes the importance of exploring alternative mechanisms beyond collider bias to better understand the underlying factors driving this paradox.

Cancer MedicineVol. 14(8)
Innsbruck Medical University (AT), Lund University (SE), Universität Innsbruck (AT), Umeå University (SE)
Cancerfonden
Good health and well-being
Openalex Percentile: Top 92%
Statistical Methods and Inference
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Collider Bias Is an Insufficient Explanation for the Inverse Obesity Paradox in Prostate Cancer — Tanja Stocks, Josef Fritz, et al. · Cancer Medicine (2025) | TGRS Research Map | TGRS