Dopaminergic medications as a preventive for myopia: insights derived from pediatric patients diagnosed with attention deficit hyperactivity disorder
Untreated ADHD in children is linked to a higher myopia risk than both non-ADHD individuals and treated ADHD patients. Dopaminergic treatments may provide a therapeutic avenue for mitigating myopia progression by enhancing dopamine signaling pathways. Key messages What is already known on this topic Dopamine release in the retina inhibits myopia progression, and ADHD is linked to dopaminergic dysfunction. ADHD treatments like methylphenidate enhance dopamine signaling, but their effect on myopia risk has not been thoroughly studied. What this study adds This study shows that untreated ADHD children have a higher risk of myopia, while dopaminergic treatments significantly reduce this risk. The use of multiple ADHD medications further strengthens the protective effect. How this study might affect research, practice or policy These findings suggest that ADHD treatments may serve as a new approach for myopia prevention, encouraging cross-field research and consideration of systemic therapies for managing comorbid conditions.
Authors
- Peng-Tai Tien
- Fuu‐Jen Tsai (ORCID: https://orcid.org/0000-0002-1373-245X)
- Lei Wan (ORCID: https://orcid.org/0000-0002-9525-3232)
- Yu-Te Huang (ORCID: https://orcid.org/0000-0002-9246-8756)
- Yih‐Dih Cheng (ORCID: https://orcid.org/0000-0003-1542-6760)
- Heng-Jun Lin (ORCID: https://orcid.org/0009-0003-1187-5494)
- Hui‐Ju Lin (ORCID: https://orcid.org/0000-0003-2606-8540)
- Yow‐Wen Hsieh (ORCID: https://orcid.org/0000-0002-0523-3482)
- Jang‐Jih Lu (ORCID: https://orcid.org/0000-0002-1692-1707)
Institutions
- Boston Children's Hospital (US)
- China Medical University (TW)
- Asia University (JP)
- China Medical University Hospital (TW)
Publication Details
- Journal
- Postgraduate Medical Journal
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1093/postmj/qgaf051
- Citations
- 1
- Primary Topic
- Ophthalmology and Visual Impairment Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- China Medical University Hospital
- China Medical University