Equivalent outcomes of human oocytes after vitrification or slow freezing with a modified rehydration protocol
The modified post-thawing rehydration method applied to slow-frozen oocytes offers benefits in terms of higher oocyte survival, fertilization, and development or activation rates, comparable to the respective measures of vitrified oocytes and, in clinical settings, high pregnancy, implantation, and birth rates. It may bring new hope to patients who have slow-frozen oocytes stored in IVF clinics.
Authors
- Karolina Hardej
- Krystyna Żyżyńska-Galeńska (ORCID: https://orcid.org/0000-0002-8251-9804)
- Ewa K. Stachowiak (ORCID: https://orcid.org/0000-0001-6088-9938)
- Katarzyna Kozioł (ORCID: https://orcid.org/0000-0002-2212-5176)
- Piotr Lewandowski (ORCID: https://orcid.org/0000-0003-4079-3001)
- K. Papis (ORCID: https://orcid.org/0000-0001-5675-4061)
Institutions
- International Institute of Molecular and Cell Biology (PL)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s12958-025-01383-2
- Citations
- 3
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 5.64