Incidence of Major Adverse Cardiovascular Events in Patients With Rheumatoid Arthritis Treated With <scp>JAK</scp> Inhibitors Compared With Biologic Disease‐Modifying Antirheumatic Drugs: Data From an International Collaboration of Registries
Observational data from the JAK-pot collaboration show no evidence of an increase in cardiovascular events during the first two years of use with JAKi compared to TNFi in the general RA population.
Authors
- Axel Finckh (ORCID: https://orcid.org/0000-0002-1210-4347)
- Delphine Sophie Courvoisier (ORCID: https://orcid.org/0000-0002-1956-2607)
- Florenzo Iannone (ORCID: https://orcid.org/0000-0003-0474-5344)
- Denis Mongin (ORCID: https://orcid.org/0000-0002-4801-8395)
- Jakub Závada (ORCID: https://orcid.org/0000-0002-9802-6545)
- Anja Strangfeld (ORCID: https://orcid.org/0000-0002-6233-022X)
- Daniela Di Giuseppe (ORCID: https://orcid.org/0000-0003-3817-8288)
- Manuel Pombo‐Suárez (ORCID: https://orcid.org/0000-0002-2524-4883)
- Johan Askling (ORCID: https://orcid.org/0000-0003-0433-0616)
- Tore Kristian Kvien (ORCID: https://orcid.org/0000-0002-8441-3093)
- Kimme L Hyrich (ORCID: https://orcid.org/0000-0001-8242-9262)
- Dan Nordström (ORCID: https://orcid.org/0000-0002-3661-6072)
- Ana Maria Rodrigues (ORCID: https://orcid.org/0000-0003-2046-8017)
- Lianne Kearsley‐Fleet (ORCID: https://orcid.org/0000-0003-0377-1575)
- Lucia Otero Varela (ORCID: https://orcid.org/0000-0002-4406-6314)
- D. Choquette (ORCID: https://orcid.org/0000-0001-6585-7695)
- Romain Guemara (ORCID: https://orcid.org/0000-0001-7776-4533)
- Doreen Huschek
- Prodromos I. Sidiropoulos (ORCID: https://orcid.org/0000-0001-9607-0326)
- Irini D. Flouri (ORCID: https://orcid.org/0000-0002-6966-1304)
- Burkhard F. Leeb (ORCID: https://orcid.org/0000-0002-2368-5036)
- Sella Aarrestad Provan (ORCID: https://orcid.org/0000-0001-5442-902X)
- Zübeyir Salis (ORCID: https://orcid.org/0000-0003-2982-4591)
- Kim Lauper (ORCID: https://orcid.org/0000-0002-4315-9009)
- Žiga Rotar (ORCID: https://orcid.org/0000-0002-9323-9189)
- Karel Pavelká (ORCID: https://orcid.org/0000-0003-1952-8422)
- Romain Aymon (ORCID: https://orcid.org/0000-0003-2854-3632)
- Cătălin Codreanu (ORCID: https://orcid.org/0000-0001-6600-9946)
- Trokovic Nina
Institutions
- University of Geneva (CH)
- University of Ljubljana (SI)
- Université de Montpellier (FR)
- Manchester Academic Health Science Centre (GB)
- Helsinki University Hospital (FI)
- Ljubljana University Medical Centre (SI)
- Karolinska Institutet (SE)
- University of Manchester (GB)
- National Institute for Health and Care Excellence (GB)
- Physiologie et Médecine Expérimentale du Coeur et des Muscles (FR)
- Institute of Rheumatology (CZ)
- Manchester University NHS Foundation Trust (GB)
- German Rheumatism Research Centre (DE)
- Complejo Hospitalario Universitario de Santiago (ES)
- Bioforschung Austria (AT)
- Sociedade Portuguesa de Cardiologia (PT)
- University Hospital of Geneva (CH)
- Arthritis UK (GB)
- Diakonhjemmet Hospital (NO)
- University Hospital of Heraklion (GR)
- Centre Hospitalier de l’Université de Montréal (CA)
- Spanish Society of Hematology and Hemotherapy (ES)
- Montreal Clinical Research Institute (CA)
- NIHR Manchester Biomedical Research Centre (GB)
- Hospital District of Helsinki and Uusimaa (FI)
- University of Bari Aldo Moro (IT)
- Charité - Universitätsmedizin Berlin (DE)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1002/art.43188
- Citations
- 13
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 21.68
Funders
- Eli Lilly and Company
- Pfizer