LASSO-derived nomogram prediction model for lymph node metastasis in colorectal cancer: a retrospective analysis
T stage, vascular tumor thrombus, PMS2, MSH2, KRAS, BRAF, and neutrophil emerged as significant risk factors for LNM in CRC, while leukocytes appeared to be protective. These findings emphasize the importance of comprehensive risk assessment and personalized therapeutic strategies in CRC management.
Authors
- Huimei Yi
- Xiyun Quan
- Ming Li (ORCID: https://orcid.org/0000-0002-2289-0222)
- Zhimin Liu (ORCID: https://orcid.org/0000-0002-7840-3315)
- Yi Deng (ORCID: https://orcid.org/0000-0001-5357-5877)
- Zhenqin Gao
Institutions
- Central South University (CN)
- Zhuzhou Central Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-04-14
- DOI
- https://doi.org/10.7717/peerj.19148
- Citations
- 1
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05