Risk and Prognostic Factors for Bloodstream Infections Due to Clonally Transmitted Acinetobacter baumannii ST2 with armA, blaOXA-23, and blaOXA-66: A Retrospective Study
The majority of <i>A. baumannii</i> strains causing BSIs in this study belonged to multidrug-resistant ST2 lineage, harboring <i>armA, bla</i>OXA-23 and <i>bla</i>OXA-66. Risk factors for secondary and mixed infections included prolonged ICU stays, mechanical ventilation (≥7 days), and open injuries, while poor prognosis was linked to severe comorbidities and extended invasive ventilation. Targeted infection control strategies are critical to reducing mechanical ventilation duration and managing open injuries in high-risk patients.
Authors
- Xiwei Liao
- Zhengnan Yang (ORCID: https://orcid.org/0000-0003-1076-3530)
- Pengfei Jiang (ORCID: https://orcid.org/0000-0003-3166-5657)
- Yan Zhang (ORCID: https://orcid.org/0000-0001-8376-3190)
- Xiaoli Cao (ORCID: https://orcid.org/0000-0001-5928-6304)
- Jie Zheng (ORCID: https://orcid.org/0000-0003-3447-9681)
- Wei Chen (ORCID: https://orcid.org/0000-0003-1526-4677)
- Chang Liu (ORCID: https://orcid.org/0009-0008-8169-4572)
- Han Shen (ORCID: https://orcid.org/0000-0002-7289-8847)
- Chao Wu (ORCID: https://orcid.org/0000-0001-8304-5973)
- Jingru Ji
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
- Northern Jiangsu People's Hospital (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/idr.s498212
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nanjing University