Rapid Detection of Anti‐IFN‐α2 Autoantibodies Using a New Automated VIDAS Assay Prototype

Autoantibodies neutralizing Type I interferons increase the risk of severe viral diseases and are linked to autoimmune conditions. The automated VIDAS assay is suitable for anti-IFN-α2 IgGs quantification, offering a swift, reliable, user-friendly, single test for clinical management.

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Institutions

Publication Details

Journal
European Journal of Immunology
Published
2025-04-01
DOI
https://doi.org/10.1002/eji.202451516
Citations
3
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
4.08

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article

Rapid Detection of Anti‐IFN‐α2 Autoantibodies Using a New Automated VIDAS Assay Prototype

Alexis Mathian, Aurore Fleurie, Paul Bastard, Laurence Generenaz et al.
3 citations
European Journal of Immunology
Monoclonal and Polyclonal Antibodies Research
4.08
article

Rapid Detection of Anti‐IFN‐α2 Autoantibodies Using a New Automated VIDAS Assay Prototype

Alexis Mathian, Aurore Fleurie, Paul Bastard, Laurence Generenaz, Karim Dorgham, Sophie Trouillet‐Assant, Adrian Gervais, Zahir Amoura, Karen Brengel‐Pesce, Jean‐Laurent Casanova, Guy Gorochov, Sylvie Pons, Valérie Guyot, Anne Puel, Nathalie Renard, Kahina Saker, Jean‐Christophe Richard, Fei Zheng, Cecile Vinit
article en
3 citations

Abstract

Autoantibodies neutralizing Type I interferons increase the risk of severe viral diseases and are linked to autoimmune conditions. The automated VIDAS assay is suitable for anti-IFN-α2 IgGs quantification, offering a swift, reliable, user-friendly, single test for clinical management.

European Journal of ImmunologyVol. 55(4)
Université Claude Bernard Lyon 1 (FR), Centre National de la Recherche Scientifique (FR), Howard Hughes Medical Institute (US), Inserm (FR), Université Paris Cité (FR), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Hospices Civils de Lyon (FR), Pitié-Salpêtrière Hospital (FR), Centre d'Immunologie et des Maladies Infectieuses (FR), Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (FR), bioMérieux (France) (FR), Centre International de Recherche en Infectiologie (FR), Institut des Maladies Génétiques Imagine (FR), Rockefeller University (US)
Institut des maladies génétiques Imagine, European Commission, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Fondation pour la Recherche Médicale, Sorbonne Université
Openalex Percentile: Top 7%
Monoclonal and Polyclonal Antibodies Research
4.08
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