Recent Updates in Nicotine Replacement Therapy for Smoking Cessation

Nicotine replacement therapy (NRT), which has been proven to increase smoking cessation success rates, can be used as both monotherapy and combination therapy.Recently, the importance of NRT methods has changed.This paper examines recent research trends on NRT, modifications of NRT in smoking cessation treatment guidelines, and practical usage methods.While most guidelines recommend varenicline as first-line treatment, a recent meta-analysis found no statistically significant difference between nicotine combination therapy (NCT) and varenicline for smoking cessation effects lasting more than six months (RR, 0.95; 95% CI, 0.73-1.22)and side effects.Additionally, some guidelines recommend NCT, albeit with restrictions, for adolescents and pregnant women.NCT can be used as an alternative to varenicline, taking into consideration smokers' preferences, nicotine dependence, and potential side effects.Adequate education on the use and side effects of NCT is necessary.