Superficial CD34 Positive Fibroblastic Tumor: A rare mesenchymal tumor of borderline malignant potential.
Superficial CD34 positive fibroblastic tumor is a rare soft tissue tumor first brought to light by Jodi M Carter in 2014. Several cases have been reported since, and they have been newly included in the recent WHO classification under the fibroblastic and myofibroblastic tumors category. It is a mesenchymal neoplasm of borderline malignant potential predominantly found in middle-aged adults with a median age of 37 years and most commonly located in the lower extremities. It is a spindle cell tumor with pleomorphic epithelioid cells, low mitotic activity, and strong diffuse positivity for CD34 on immunohistochemistry. The prognosis is good post excision but needs long-term follow-up since few cases revealed recurrences and lymph node metastases. As far as we know, only 64 cases have been documented thus far. We have reported a 63-year female with essential histological features of superficial CD34 positive fibroblastic tumor with no local recurrence or metastasis to date.
Authors
- Jayashri Chaudhari (ORCID: https://orcid.org/0000-0002-1572-6942)
- Manisha Khare
- Pradnya Kamble (ORCID: https://orcid.org/0009-0009-3253-0675)
Institutions
- Cooper Hospital (IN)
Publication Details
- Journal
- Journal of Pathology of Nepal
- Published
- 2024-12-31
- DOI
- https://doi.org/10.3126/jpn.v14i2.64485
- Primary Topic
- Soft tissue tumor case studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00