Monofluoromethylation of acyl chlorides and chloroformates employing fluorobis(phenylsulfonyl)methane. Synthesis of monofluoromethyl ketones <i>via</i> selective zinc-mediated reductive desulfonylation
A high yielding protocol for the synthesis of valuable monofluoromethyl ketones (MFMK) utilizing fluorobis(phenylsulfonyl)methane (FBSM) is presented.
Authors
- G. K. Surya Prakash (ORCID: https://orcid.org/0000-0002-6350-8325)
- Thomas Saal (ORCID: https://orcid.org/0000-0001-8878-1849)
- Alexander Knieb (ORCID: https://orcid.org/0000-0002-0143-2986)
- Xanath Ispizua‐Rodriguez (ORCID: https://orcid.org/0000-0003-4940-501X)
- P. Purushothama Rao
Institutions
- University of Southern California (US)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00451a
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Loker Hydrocarbon Research Institute, University of Southern California