Fractional Excretion of Sodium: A Simple Tool for the Differential Diagnosis of Acute Kidney Injury in ICU Patients

Our findings focus on the clinical value of FENa as indicators in the early discrimination of ATN from PRA in ICU patients with AKI, facilitating timely and targeted interventions based on the underlying etiology,This cross-sectional research was performed from May 2023 to January 2024 and one hundred and six participants were included in the analysis. All participants' demographic and laboratory data are used to determine the cause of AKI as well as the clinical evaluation. These data were utilized to calculate FENa,Our analysis includes one hundred and six participants, 47 males and 59 females, they were separated into two groups (n=53 each): (PRA) group and (ATN) group. The mean age in the PRA group was 48.91 ± 11.41 while in the ATN group 49.55 ± 10.38. We found that FENa was significantly increased in the ATN group than PRA group (P value 0.044 and <0.001 correspondingly). FENa can significantly predict ATN (P value 0.041 and P value <0.001 individually) at different cut-off.

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Publication Details

Journal
Aswan University Medical Journal/Aswan University Medical Journal
Published
2025-04-07
DOI
https://doi.org/10.21608/aumj.2025.350323.1179
Primary Topic
Renal function and acid-base balance
Type
article
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article

Fractional Excretion of Sodium: A Simple Tool for the Differential Diagnosis of Acute Kidney Injury in ICU Patients

Mohamed Ali Bakry
Aswan University Medical Journal/Aswan University Medical Journal
Renal function and acid-base balance
article

Fractional Excretion of Sodium: A Simple Tool for the Differential Diagnosis of Acute Kidney Injury in ICU Patients

Mohamed Ali Bakry
article en

Abstract

Our findings focus on the clinical value of FENa as indicators in the early discrimination of ATN from PRA in ICU patients with AKI, facilitating timely and targeted interventions based on the underlying etiology,This cross-sectional research was performed from May 2023 to January 2024 and one hundred and six participants were included in the analysis. All participants' demographic and laboratory data are used to determine the cause of AKI as well as the clinical evaluation. These data were utilized to calculate FENa,Our analysis includes one hundred and six participants, 47 males and 59 females, they were separated into two groups (n=53 each): (PRA) group and (ATN) group. The mean age in the PRA group was 48.91 ± 11.41 while in the ATN group 49.55 ± 10.38. We found that FENa was significantly increased in the ATN group than PRA group (P value 0.044 and <0.001 correspondingly). FENa can significantly predict ATN (P value 0.041 and P value <0.001 individually) at different cut-off.

Aswan University Medical Journal/Aswan University Medical Journal Vol. 0(0)
Aswan University (EG)
Openalex Percentile: Top 91%
Renal function and acid-base balance
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