Gut virome profile in new onset treatment naïve Saudi children with ulcerative colitis
We found a significantly altered bacteriophage signature in children with new onset, treatment naïve UC in Saudi children, a Middle Eastern population. These changes differed from previously reported Western UC cases, indicating that demographic bias needs to be considered when developing microbiota-based diagnostics and therapeutic applications for non-Western populations.
Authors
- Mohammad El Mouzan
- Shyam Badu
- Mohammad Al Mofarreh (ORCID: https://orcid.org/0000-0001-5426-9425)
- Ahmed Al Sarkhy (ORCID: https://orcid.org/0000-0002-1424-5784)
- Tor Savidge (ORCID: https://orcid.org/0000-0001-5716-5357)
- Badr Alsaleem
- Abdulrahman Almasood
- Asaad Assiri (ORCID: https://orcid.org/0000-0003-3357-5794)
Institutions
- Baylor College of Medicine (US)
- King Fahd Medical City (SA)
- King Saud University (SA)
- Texas Children's Hospital (US)
Publication Details
- Journal
- Saudi Journal of Gastroenterology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.4103/sjg.sjg_24_25
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81