Assessing the potential of nifedipine and resveratrol to enhance ovarian viability in conjunction with detorsion treatment: A rat ovarian torsion model study
Nifedipine and resveratrol treatments did not influence AMH levels and antioxidant-oxidant system parameters in rats exposed to I/R injury. However, nifedipine had a positive effect on AMH expression and secondary follicle count, and resveratrol decreased the expression of VEGFR-2 in tissues, which can be an indicator of their clinical potential.
Authors
- Ahmet Erdem (ORCID: https://orcid.org/0000-0001-9944-6894)
- Erhan Demirdağ (ORCID: https://orcid.org/0000-0003-4599-3854)
- Mehmet Erdem (ORCID: https://orcid.org/0000-0002-1939-7138)
- Cengiz Karakaya (ORCID: https://orcid.org/0000-0002-0399-9150)
- Aydan Sezgin (ORCID: https://orcid.org/0000-0002-3711-5747)
- Asiye Aslı Emniyet Sert (ORCID: https://orcid.org/0000-0001-5980-8694)
- Münire Funda Cevher Akdulum (ORCID: https://orcid.org/0000-0003-2285-7112)
- Gülnur Take Kaplanoğlu (ORCID: https://orcid.org/0000-0002-3661-3488)
- Mesut Öktem (ORCID: https://orcid.org/0000-0002-5555-8189)
Institutions
- Gazi University (TR)
Publication Details
- Journal
- Journal of Turkish Society of Obstetric and Gynecology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.4274/tjod.galenos.2025.30161
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00