CDK4/6 inhibitor-associated vortex keratopathy: a case report

This case demonstrates the ocular characteristics and novel findings of corneal confocal microscopy of CDK4/6 inhibitor-related vortex keratopathy. Our findings increase the understanding of the pathophysiological mechanisms of drug-induced vortex keratopathy and increase our awareness of ocular manifestations in patients receiving novel anticancer drugs.

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Publication Details

Journal
BMC Ophthalmology
Published
2025-04-14
DOI
https://doi.org/10.1186/s12886-025-04043-6
Citations
1
Primary Topic
Drug-Induced Ocular Toxicity
Type
article
Field-Weighted Citation Impact
1.71
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article

CDK4/6 inhibitor-associated vortex keratopathy: a case report

Xinhan Cui, Yan Wang, Xinghuai Sun, Lian Shu
1 citations
BMC Ophthalmology
Drug-Induced Ocular Toxicity
1.71
article

CDK4/6 inhibitor-associated vortex keratopathy: a case report

Xinhan Cui, Yan Wang, Xinghuai Sun, Lian Shu
article en
1 citations

Abstract

This case demonstrates the ocular characteristics and novel findings of corneal confocal microscopy of CDK4/6 inhibitor-related vortex keratopathy. Our findings increase the understanding of the pathophysiological mechanisms of drug-induced vortex keratopathy and increase our awareness of ocular manifestations in patients receiving novel anticancer drugs.

BMC OphthalmologyVol. 25(1)
Eye & ENT Hospital of Fudan University (CN)
Openalex Percentile: Top 20%
Drug-Induced Ocular Toxicity
1.71
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CDK4/6 inhibitor-associated vortex keratopathy: a case report — Xinhan Cui, Yan Wang, et al. · BMC Ophthalmology (2025) | TGRS Research Map | TGRS