Association of Triglyceride-Glucose Index with Severity of Myocardial Ischemia According to Myocardial Perfusion Imaging

Objectives: To evaluate the relationship between ischemia detected by myocardial perfusion imaging (MPI) and triglyceride-glucose (TyG) index. Design: A cross-sectional study. Settings: All patients were referred to a tertiary hospital and underwent myocardial perfusion scanning. Participants: One hundred fifteen patients who underwent myocardial perfusion scanning. Outcome Measures: The formula LN [TG (mg/dL)×FBG (mg/dL)/2] was used to calculate the TyG index. The presence, severity, and extent of ischemia were determined based on the MPI reports. Results: The data from 115 patients, including 22 men (19.1%), with a mean age of 53.67±11.57 years, were analyzed in this study. The TyG index showed a significant association with the severity of ischemia as reported by MPI, increasing from 8.58±0.45 in non-ischemic patients to 9.6±0.33 in patients with severe ischemia. The final analysis revealed that a TyG index above 9.15, with a sensitivity of 68.4% and specificity of 84.2%, could predict a summed difference score of>0. Conclusions: A significant correlation was detected between the TyG index and ischemia using MPI.