Effectiveness of a Model of Care Based on Fibrosis-4 and Liver Stiffness Measurement for the Screening of Patients With Type 2 Diabetes Mellitus at Risk of Advanced Liver Disease: Results From an Italian Prospective Multicenter Study
In diabetes clinics, the 2-tier screening using FIB-4 and VCTE is effective for the identification of patients with T2DM to be referred to hepatologists. VCTE referral may be considered for patients with overweight/obesity and elevated alanine aminotransferase classified as at low risk of advanced liver fibrosis by FIB-4.
Authors
- Gian Paolo Caviglia (ORCID: https://orcid.org/0000-0002-0529-9481)
- Chiara Rosso (ORCID: https://orcid.org/0000-0001-6518-7089)
- Francesca Marchignoli (ORCID: https://orcid.org/0000-0002-4862-1274)
- Maria Letizia Petroni (ORCID: https://orcid.org/0000-0002-7040-6466)
- Gianluca Svegliati‐Baroni (ORCID: https://orcid.org/0000-0003-4399-3359)
- Federica Barutta (ORCID: https://orcid.org/0000-0001-9319-5123)
- Elisabetta Bugianesi (ORCID: https://orcid.org/0000-0002-0502-4381)
- Luca Valenti (ORCID: https://orcid.org/0000-0001-8909-0345)
- Roberta D’Ambrosio (ORCID: https://orcid.org/0000-0003-0019-1153)
- Riccardo Perbellini (ORCID: https://orcid.org/0000-0002-4412-1256)
- Angelo Armandi (ORCID: https://orcid.org/0000-0002-7245-4445)
- Salvatore Petta (ORCID: https://orcid.org/0000-0002-0822-9673)
- Giulia Periti (ORCID: https://orcid.org/0009-0005-1265-4583)
- Lucia Brodosi (ORCID: https://orcid.org/0000-0002-7735-7847)
- Grazia Pennisi (ORCID: https://orcid.org/0000-0001-9518-4751)
- Carlo Ciccioli
- Maria Eva Argenziano (ORCID: https://orcid.org/0000-0001-9213-1494)
- Gabriella Gruden (ORCID: https://orcid.org/0000-0001-8906-9589)
- Loris Pironi (ORCID: https://orcid.org/0000-0002-1773-8330)
- Arianna Ferro (ORCID: https://orcid.org/0000-0002-1450-7035)
- Pietro Lampertico (ORCID: https://orcid.org/0000-0002-1026-7476)
- Alessandra Sagripanti
Institutions
- Marche Polytechnic University (IT)
- University of Applied Sciences Mainz (DE)
- University of Milan (IT)
- Johannes Gutenberg University Mainz (DE)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Ospedale Maggiore (IT)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Institute of Neurological Sciences (IT)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Turin (IT)
- University of Palermo (IT)
- University of Bologna (IT)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.14309/ajg.0000000000003493
- Citations
- 5
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77