Double-Blind, Randomized, Placebo-Controlled, Crossover Study of Oral Cannabidiol and Tetrahydrocannabinol for Essential Tremor

This double-blind, randomized, placebo-controlled efficacy and tolerability pilot trial did not detect any signals of efficacy of oral cannabidiol and tetrahydrocannabinol in reducing essential tremor amplitude using either digital outcome measures or clinical rating scales. The oral cannabinoids were well-tolerated by most (five out of seven) participants.

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Publication Details

Journal
Tremor and Other Hyperkinetic Movements
Published
2025-01-01
DOI
https://doi.org/10.5334/tohm.1005
Primary Topic
Cannabis and Cannabinoid Research
Type
article
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article

Double-Blind, Randomized, Placebo-Controlled, Crossover Study of Oral Cannabidiol and Tetrahydrocannabinol for Essential Tremor

Brenton A. Wright, F. Xavier Castellanos, Fatta B. Nahab, Jeremiah D. Momper et al.
1 links
Tremor and Other Hyperkinetic Movements
Cannabis and Cannabinoid Research
article

Double-Blind, Randomized, Placebo-Controlled, Crossover Study of Oral Cannabidiol and Tetrahydrocannabinol for Essential Tremor

Brenton A. Wright, F. Xavier Castellanos, Fatta B. Nahab, Jeremiah D. Momper, Katherine Longardner, Rhea Gandhi, Bin Tang, Shen Qian
article en

Abstract

This double-blind, randomized, placebo-controlled efficacy and tolerability pilot trial did not detect any signals of efficacy of oral cannabidiol and tetrahydrocannabinol in reducing essential tremor amplitude using either digital outcome measures or clinical rating scales. The oral cannabinoids were well-tolerated by most (five out of seven) participants.

Tremor and Other Hyperkinetic MovementsVol. 15(1)
University of California San Diego (US), New York University (US)
Good health and well-being
Openalex Percentile: Top 91%
Cannabis and Cannabinoid Research
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Double-Blind, Randomized, Placebo-Controlled, Crossover Study of Oral Cannabidiol and Tetrahydrocannabinol for Essential Tremor — Brenton A. Wright, F. Xavier Castellanos, et al. · Tremor and Other Hyperkinetic Movements (2025) | TGRS Research Map | TGRS