EVALUATION OF THE EMBRYOTOXIC AND TERATOGENIC EFFECTS OF THE VETERINARY DRUG "IVERGEL"

This article presents the results of a study of the embryotoxic and teratogenic effects of the Ivergel antiparasitic veterinary drug, the main active ingredient of which is ivermectin. The study objective was to evaluate the safety of using an antiparasitic veterinary drug in pregnant animals. For this purpose, the drug was administered at a dosage of 0.2 mg/ kg during different periods of pregnancy, after which the condition of the embryos and newborns was assessed. The results showed that the administration of Ivergel does not lead to an increase in fetal mortality, the frequency of resorption or the occurrence of congenital anomalies in the offspring. The fetal weight in the experimental group was comparable to the control group, indicating the absence of embryotoxic effects. The results obtained are important for veterinary practice, as they confirm the safety of using the Ivergel in pregnant animals while observing the recommended dosages. This enables to use effectively this drug to control parasites without the risk of negative effects on developing embryos. However, the study highlights the need for further research to assess potential risks when therapeutic doses are exceeded or when the drug is used chronically.