Blunt liver trauma: from non-operative management to transplantation. Systematic review and meta-analysis. Part I: primary control point - mortality

Introduction. The high incidence of blunt liver injuries, general and postoperative mortality necessitate a search for optimal treatment options of the condition. Аim. To conduct a systematic literature review and meta-analysis and compare various treatment options for patients with blunt liver injury. Methods. A systematic search for non–randomized studies was conducted from 01 October 2015, a systematic search for randomized studies was conducted without time limits, until February 29, 2024. Results. There is a clear trend towards non-surgical management of hemodynamically stable or stabilized patients, and in case of hemodynamic instability, the use of liver tamponade followed by angioembolization. Conclusion. A larger number of well-planned randomized clinical trials are required to concretize the surgical approach to patients with liver injury.