AI-Powered Drug Classification and Indication Mapping for Pharmacoepidemiologic Studies: Prompt Development and Validation
GPT-4o offers cost-effective drug classification from RWD without violating any terms of service. Using a chain-of-thought prompting technique, GPT-4o can reason about drug dosages that affect the class. The wide accessibility of LLMs gives every research team the ability to classify drugs at scale, a key prerequisite of pharmacoepidemiologic research.
Authors
- Isaac R. Rodriguez‐Chavez (ORCID: https://orcid.org/0000-0003-1787-8381)
- Benjamin Alexander Ogorek
- Thomas Patrick Rhoads
- Eric Scott Finkelman
Institutions
- Spencer Foundation (US)
- Hydrosolutions (Switzerland) (CH)
Publication Details
- Journal
- JMIR AI
- Published
- 2025-04-14
- DOI
- https://doi.org/10.2196/65481
- Citations
- 1
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.50