THEMIS2 contributes to ovarian cancer metastasis via DOCK4-mediated activation of Rap1 signaling
THEMIS2 may serve as a predictive biomarker for OC prognosis, and targeting the Rap1 signaling pathway with specific inhibitors represents a promising therapeutic strategy for OC treatment.
Authors
- Hui Zheng (ORCID: https://orcid.org/0000-0003-2930-4641)
- Katie Zhou (ORCID: https://orcid.org/0000-0001-7431-9979)
- Xiaolu Ma (ORCID: https://orcid.org/0000-0003-3960-5720)
- Yanan Tian (ORCID: https://orcid.org/0000-0002-2344-7484)
- Tianqing Yan (ORCID: https://orcid.org/0000-0003-3410-0395)
- Suhong Xie (ORCID: https://orcid.org/0000-0003-1044-9373)
- Ling Hu (ORCID: https://orcid.org/0000-0001-7318-5091)
- Lin Guo (ORCID: https://orcid.org/0000-0002-1692-0667)
- Yanchun Wang
- Ying Tong (ORCID: https://orcid.org/0000-0002-8460-0585)
- Renquan Lu (ORCID: https://orcid.org/0000-0002-3199-2271)
Institutions
- Shanghai Medical College of Fudan University (CN)
Publication Details
- Journal
- Cellular Oncology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1007/s13402-025-01057-6
- Citations
- 4
- Primary Topic
- Microtubule and mitosis dynamics
- Type
- article
- Field-Weighted Citation Impact
- 4.61
Funders
- National Natural Science Foundation of China
- Fudan University
- Science and Technology Commission of Shanghai Municipality