Integrating network toxicology and Mendelian randomization to uncover the role of AHR in linking air pollution to male reproductive health
By integrating network toxicology, MR, and molecular docking analysis, this study highlights the critical role of AHR as a molecular bridge between air pollution and MRH. These findings provide novel molecular insights into the impact of Aps on MRH.
Authors
- Qingfu Deng (ORCID: https://orcid.org/0009-0008-4836-9495)
- Xinyao Zhu (ORCID: https://orcid.org/0000-0002-4507-0833)
- Jinghong Yang
- Qilong Wu
- Chunyang Meng (ORCID: https://orcid.org/0000-0002-3334-9503)
- Tao Zhou (ORCID: https://orcid.org/0000-0003-1295-8331)
- Yang Zeng (ORCID: https://orcid.org/0000-0002-3651-042X)
- Zhiyu Liu (ORCID: https://orcid.org/0000-0002-6024-7836)
- Yuqi Li (ORCID: https://orcid.org/0000-0003-4629-4027)
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Reproductive Toxicology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.reprotox.2025.108918
- Citations
- 9
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 10.80
Funders
- Luzhou Science and Technology Bureau