PHARMACEUTICO-ANALYTICAL STUDY OF HARATALA MARITA YASADA BAHSMA: A REVALIDATION ON CLASSICAL AND CONTEMPORARY METHOD

Rasasastra has laid much more stress on Rasayana concept of Ayurveda and which when administered orally was found to prevent diseases related to age. Bhasmas are being practiced safely in therapeutics; concerns are being arising on the safety issues in the recent past. Yasada bhasma was prepared by classical bhasmeekarana (incineration) method as per reference of Rasa Tarangini. Haratala used in the marana were processed with suitable sodhana method. Bhasma was prepared by 3 step process that is sodhana, jarana and marana. Three samples of Yasada bhasma was prepared to confirm the study reproducibility. Quality control parameters were analyzed both chemically as well as with modern parameters. Raw material quality was assessed through grahya lakshana, and those during the procedure of incineration via various bhasma pareekshas, end products through pH, LOD, Total ash, acid insoluble ash, water soluble ash and instrumental analysis like XRD, SEM, and EDAX. On basis of comparing samples with analytical parameters like NPST and XRD etc. best sample of Yasada bhasma has been selected. Among which the classically incinerated samples are found to be of standard quality, showing hexagonal ZnO crystalline phase. The more symmetric XRD spectra and symmetry of particles and reduced particle size was noted in classically prepared bhasma. EDAX revealed difference in concentration of zinc and oxygen in both the samples. Based on the empirical evidence and classical baseline principles, logical reasoning was done to end up in an accurate report in present study.