Hemodynamic overload of effort testing for breast cancer patients

Introduction: There is a link between breast cancer and cardiovascular diseases. However, stress test comparisons in breast cancer patients have not been established in the field of exercise prescription. Objective: This study aimed at comparing the hemodynamic responses of the Six-minute Walk Test (SMWT) with the Modified Naughton Test (MNT) in women with and without breast cancer. Methods: Participants included 42 women with breast cancer and 36 women with other chronic noncommunicable diseases. All women underwent hemodynamic evaluations, heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure, and rating of perceived exertion (RPE) of the SMWT and MNT, measured before, immediately after and five min after testing. Results: The group with breast cancer exhibited lower DBP (p=0.020) before the SMWT, lower DBP(p=0.008) and HR (p=0.008) immediately after the MNT. In addition, the women with breast cancer the MNT occurred a peak of SBP (stage nine), as also higher double product (DP) (p<0.001), DP reserve (p<0.001), Δ% of HR, and anticipation of deflection point of HR (6 km/h). Conclusion: SMWT seemed to be more conservative in generating lower peakhemodynamic variables, while MNT, although had increased both the DP, DP reserve and Δ% of HR, showed better hemodynamic control, with the possibility to detect the deflection point of the HR, mainly for women with breast cancer.