Donor-derived cell-free DNA testing in pediatric kidney transplant recipients: indications and clinical utility
Elevated dd-cfDNA is strongly associated with BPAR, class II dnHLAab and DSAs. Conversely, low values are observed in immunoquiescent states. Dd-cfDNA can be a useful tool for non-invasive clinical decision-making.
Authors
- Jayanthi Chandar (ORCID: https://orcid.org/0000-0002-2859-4184)
- Marissa J. DeFreitas (ORCID: https://orcid.org/0000-0001-9331-1905)
- Vaka K. Sigurjonsdottir (ORCID: https://orcid.org/0000-0003-2776-4601)
- M. Zhou (ORCID: https://orcid.org/0009-0003-1430-0485)
- Tara B. Gavcovich (ORCID: https://orcid.org/0009-0004-3991-1618)
- Renata Glehn-Ponsirenas (ORCID: https://orcid.org/0000-0001-9521-7373)
- George W. Burke (ORCID: https://orcid.org/0000-0002-6888-2842)
Institutions
- University of Miami (US)
- Veterans Health Administration (US)
- Jackson Health System (US)
- Miami Transplant Institute (US)
- Data Management (Italy) (IT)
Publication Details
- Journal
- Pediatric Nephrology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1007/s00467-025-06770-w
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00