In vivo <scp> <sup>2</sup> H </scp> ‐ <scp>MR</scp> spectroscopy and imaging of hepatic metabolic formation of trimethylamine‐N‐oxide
This work shows the ability to use <sup>2</sup>H-MR-based methodologies to spatially monitor the TMA-to-TMAO metabolic pathway in vivo, and thus should be explored further to investigate the role of TMAO in diverse pathologies.
Authors
- Amnon Bar‐Shir (ORCID: https://orcid.org/0000-0003-1431-0221)
- Elton Tadeu Montrazi (ORCID: https://orcid.org/0000-0001-5898-1153)
- Hyla Allouche‐Arnon
- Robin A. de Graaf (ORCID: https://orcid.org/0000-0002-6570-7010)
- Talia Harris (ORCID: https://orcid.org/0009-0008-8230-2753)
- Hadar Dessau
Institutions
- Yale University (US)
- Resonance Research (United States) (US)
- Weizmann Institute of Science (IL)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1002/mrm.30531
- Citations
- 1
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- Minerva Foundation
- Israel Science Foundation