Correlation Between Leukocyte and Platelet in Patients with Degree 1 and 2 Dengue Fever Ajibarang Hospital

Background: Dengue Hemorrhagic Fever (DHF) is characterized with main clinical features including fever, bleeding, hepatomegaly, abdominal pain, vomiting and hypothermia, and severe plasma leakage. Leukopenia, thrombocytopenia, and increased hematocrit values can be found as abnormal blood profile. Leukocytes are often ignored even though viral infections are usually accompanied by leukopenia. Therefore, researchers wanted to know whether leukopenia could be used as a predictor of worsening of thrombocytopenia in dengue fever patients. Aim: The purpose of this study was to determine the relationship between leukocytes count and platelets count in DHF grades 1 and 2 patients at the Ajibarang Regional General Hospital. Method: Analytical observational quantitative research method with a cross-sectional study design in patients with Dengue Hemorrhagic Fever grades 1 and 2 at the Ajibarang Regional General Hospital was carried out in March-May 2022. The variables of leukocyte count and platelet count were obtained from complete blood count by Sysmex XS series. Spearman’s test was used to analyze the relationship between two variables. Result: There was significant difference in hemoglobin, hematocrit, and thrombocyte level between DHF Grade 2 and Grade 1 (p 0.05). Spearman Test showed p= 0,833 between leukocytes and platelets count (p 0.05). Conclusion: There is no relationship between leukocyte count and platelet count in patients with dengue hemorrhagic fever grades 1 and 2.