Cis-Regulatory Alterations in <i>FOXP4</i> Modulate Esophageal Cancer Susceptibility Induced by Chronic Alcohol Exposure
An enhancer variant in FOXP4 mediates the interplay between alcohol consumption, epigenetic alterations, and esophageal carcinogenesis, which could inform development of early detection and prevention strategies.
Authors
- Jiang Chang (ORCID: https://orcid.org/0000-0001-8551-9458)
- Linglong Gu (ORCID: https://orcid.org/0009-0000-9493-5349)
- Jixuan Ma
- Miaoxin Pan
- Xinying Yue (ORCID: https://orcid.org/0000-0003-0434-521X)
- Chaolong Wang (ORCID: https://orcid.org/0000-0003-3945-1012)
- Sijie Niu
- Yuqian Tan (ORCID: https://orcid.org/0009-0005-5419-7683)
- Zifei Yang
- Yueping Li
- Shasha Liu
- Lina Song
- Yutong Wu
Institutions
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Cancer Research
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1158/0008-5472.can-24-3839
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00