ACO/ARO/AIO-22 – External beam radiotherapy combined with endorectal high-dose-rate brachytherapy in elderly and frail patients with rectal cancer: A prospective multicentre trial of the German Rectal Cancer Study Group
The ACO/ARO/AIO-22 prospective multicentre trial will evaluate organ preservation rates and QoL after combining EBRT with endorectal HDR-BT in elderly and/or frail patients with rectal cancer.<b>Trial Registration:</b>Clinicialtrials.gov number: NCT06729645.
Authors
- Silke Tribius (ORCID: https://orcid.org/0000-0001-7754-0257)
- Frank A. Giordano (ORCID: https://orcid.org/0000-0001-5243-4781)
- Michael B. Ghadimi (ORCID: https://orcid.org/0000-0001-8208-1526)
- Dirk Arnold (ORCID: https://orcid.org/0000-0002-5325-8182)
- Heinz Schmidberger
- Eleni Gkika (ORCID: https://orcid.org/0000-0001-5455-252X)
- Ricarda Merten
- Pompiliu Piso (ORCID: https://orcid.org/0000-0001-7146-4505)
- Simon Kirste (ORCID: https://orcid.org/0000-0001-5556-6069)
- Claus Michael Rödel (ORCID: https://orcid.org/0009-0006-1777-2359)
- Felix Popp (ORCID: https://orcid.org/0000-0002-1690-6777)
- Emmanouil Fokas (ORCID: https://orcid.org/0000-0003-1601-6165)
- Hendrik Dapper
- Georg Dieplinger
- Thomas Brunner (ORCID: https://orcid.org/0000-0002-1594-4712)
- Bülent Polat (ORCID: https://orcid.org/0000-0003-4677-424X)
- Anca-Ligia Grosu (ORCID: https://orcid.org/0000-0003-2255-2255)
- Christiane J. Bruns (ORCID: https://orcid.org/0000-0001-6590-8181)
- Maximilian Fleischmann
- Ralf‐Dieter Hofheinz (ORCID: https://orcid.org/0000-0001-5972-8504)
- Tim Friede (ORCID: https://orcid.org/0000-0001-5347-7441)
- Gerhard G. Grabenbauer (ORCID: https://orcid.org/0000-0003-1367-5536)
- Nikolaos Tselis
- Markus Diefenhardt (ORCID: https://orcid.org/0000-0002-9042-9729)
- Thomas Kuhnt
- Juliane Hörner‐Rieber (ORCID: https://orcid.org/0000-0003-3911-4438)
- Georg Wurschi (ORCID: https://orcid.org/0000-0002-8751-9862)
- Stefan A. Koerber (ORCID: https://orcid.org/0000-0003-3958-9361)
- Thomas Zander (ORCID: https://orcid.org/0000-0002-4266-6818)
- Stefan Rieken (ORCID: https://orcid.org/0009-0000-7018-2856)
- Christian Langer (ORCID: https://orcid.org/0000-0003-0698-3223)
- Ursula Nestle
- Matthias Geiger
- Johannes Claßen
- Christian Weiß
- Felix Bock
Institutions
- Goethe University Frankfurt (DE)
- University of Freiburg (DE)
- German Cancer Research Center (DE)
- University of Cologne (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Johannes Gutenberg University Mainz (DE)
- Medical University of Graz (AT)
- Heidelberg University (DE)
- University of Würzburg (DE)
- University Hospital Bonn (DE)
- University Medical Center Freiburg (DE)
- University Hospital Heidelberg (DE)
- Kempten University of Applied Sciences (DE)
- Asklepios Klinik Altona (DE)
- Düsseldorf University Hospital (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Klinikum Darmstadt (DE)
- Kliniken Maria Hilf (DE)
- St. Vincentius-Kliniken (DE)
- Universitätsmedizin Göttingen (DE)
- Asklepios Klinik St. Georg (DE)
- Krankenhaus Barmherzige Brüder (DE)
- Klinikum Coburg (DE)
- Jena University Hospital (DE)
- BOS (Germany) (DE)
- University Hospital Cologne (DE)
- University Medical Centre Mannheim (DE)
- Frankfurt Cancer Institute (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Heinrich Heine University Düsseldorf (DE)
- University of Rostock (DE)
- University of Göttingen (DE)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.ctro.2025.100958
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Krebshilfe