Intracranial malignant melanotic nerve sheath tumor: illustrative case

Melanotic schwannomas have a malignant propensity despite their benign morphology. Immunohistochemical analysis helps confirm the diagnosis of melanotic schwannoma. This is the 21st documented case of an intracranial MMNST, and, given the rarity of the tumor, there is scope for further research and studies on the role of radiotherapy in the management of these tumors. https://thejns.org/doi/10.3171/CASE24473.

Authors

Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-04-14
DOI
https://doi.org/10.3171/case24473
Citations
2
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
2.78
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article

Intracranial malignant melanotic nerve sheath tumor: illustrative case

Mahendra Madesh, Sruthi Pericherla, Swapnesh Chindhalore
2 citations
Journal of Neurosurgery Case Lessons
Neurofibromatosis and Schwannoma Cases
2.78
article

Intracranial malignant melanotic nerve sheath tumor: illustrative case

Mahendra Madesh, Sruthi Pericherla, Swapnesh Chindhalore
article en
2 citations

Abstract

Melanotic schwannomas have a malignant propensity despite their benign morphology. Immunohistochemical analysis helps confirm the diagnosis of melanotic schwannoma. This is the 21st documented case of an intracranial MMNST, and, given the rarity of the tumor, there is scope for further research and studies on the role of radiotherapy in the management of these tumors. https://thejns.org/doi/10.3171/CASE24473.

Journal of Neurosurgery Case LessonsVol. 9(15)
No poverty
Openalex Percentile: Top 11%
Neurofibromatosis and Schwannoma Cases
2.78
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Intracranial malignant melanotic nerve sheath tumor: illustrative case — Mahendra Madesh, Sruthi Pericherla, et al. · Journal of Neurosurgery Case Lessons (2025) | TGRS Research Map | TGRS