Drug‐induced liver injury due to granulocyte colony‐stimulating factor in a healthy donor for allogeneic peripheral blood stem cell transplantation

As G-CSF allergy screening is not mandatory in current Japanese protocols, DILI due to G-CSF could present a risk during PBSCH. This case emphasizes the importance of vigilant monitoring and comprehensive risk assessment to ensure the safety of healthy donors.

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Publication Details

Journal
Vox Sanguinis
Published
2025-04-14
DOI
https://doi.org/10.1111/vox.70032
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
0.00
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Drug‐induced liver injury due to granulocyte colony‐stimulating factor in a healthy donor for allogeneic peripheral blood stem cell transplantation

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Drug‐induced liver injury due to granulocyte colony‐stimulating factor in a healthy donor for allogeneic peripheral blood stem cell transplantation

Yoshiki Okuyama, Takashi Toya, Kazuki Inai, Yuho Najima, Naoki Shingai, Noriko Doki, Yasutaka Masuda, Hiroaki Shimizu, Satoshi Sakai, Shuhei Kurosawa, Kairi Kojo, Masamichi Kimura, Atsushi Jinguji, Chika Kato, Yukie Terasaki, Ryoji Yamakawa, Masashi Shimabukuro, Fumihiko Ouchi, Yasutaka Sadaga, Kaori Kondo, Kana Kato, Kyoko Haraguchi, Hiroki Hatsusawa
article en

Abstract

As G-CSF allergy screening is not mandatory in current Japanese protocols, DILI due to G-CSF could present a risk during PBSCH. This case emphasizes the importance of vigilant monitoring and comprehensive risk assessment to ensure the safety of healthy donors.

Vox SanguinisVol. 120(7)
Tokyo Metropolitan Komagome Hospital (JP)
Good health and well-being
Openalex Percentile: Top 90%
Drug-Induced Hepatotoxicity and Protection
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