Gene signatures and immune correlations in Parkinson’s disease Braak stages

This study revealed the Braak stage-related gene signatures in PD and identified CPLX2 as a novel Braak stages-related hub gene in PD, which provided a novel target for future therapeutic interventions and disease markers. The specific molecular mechanism of CPLX2 in PD remained to be further clarified.

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Publication Details

Journal
European journal of medical research
Published
2025-04-15
DOI
https://doi.org/10.1186/s40001-025-02554-y
Citations
2
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
2.78
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article

Gene signatures and immune correlations in Parkinson’s disease Braak stages

Yan Guo, Sun Ruixue
2 citations
European journal of medical research
Parkinson's Disease Mechanisms and Treatments
2.78
article

Gene signatures and immune correlations in Parkinson’s disease Braak stages

Yan Guo, Sun Ruixue
article en
2 citations

Abstract

This study revealed the Braak stage-related gene signatures in PD and identified CPLX2 as a novel Braak stages-related hub gene in PD, which provided a novel target for future therapeutic interventions and disease markers. The specific molecular mechanism of CPLX2 in PD remained to be further clarified.

European journal of medical researchVol. 30(1)
Community Health Center (US)
Zero hunger
Openalex Percentile: Top 11%
Parkinson's Disease Mechanisms and Treatments
2.78
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Gene signatures and immune correlations in Parkinson’s disease Braak stages — Yan Guo, Sun Ruixue · European journal of medical research (2025) | TGRS Research Map | TGRS