Characteristics of cortical thickness in treated HIV-infected individuals with and without cognitive impairment
The cortical thickness thinning was observed in the frontal and limbic systems in both ANI and CI. Meanwhile, the thickening of the insular cortex may represent mild neuroinflammation or a transient compensatory mechanism. This study provides new insights into the neural mechanisms underlying HIV-related cognitive impairment and highlights the importance of cortical thickness alteration patterns when assessing cognitive function of PLWH.
Authors
- Hongjun Li (ORCID: https://orcid.org/0000-0003-1102-6225)
- Jie Lu (ORCID: https://orcid.org/0000-0003-0425-3921)
- Xire Aili
- Zhang Miao
- Ruili Li (ORCID: https://orcid.org/0000-0003-4396-2034)
- Guang‐Xue Liu
Institutions
- Capital Medical University (CN)
- Peking University (CN)
- Beijing YouAn Hospital (CN)
- Beijing Advanced Sciences and Innovation Center (CN)
- Beihang University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s40001-025-02555-x
- Citations
- 3
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.11
Funders
- National Natural Science Foundation of China