An examination of symptoms, function and quality of life as conjoint clinical outcome domains for treatment-resistant depression
Symptoms, function and QoL capture distinct, clinically significant and valid outcomes that identify persons with markedly TRD with a range of clinically meaningful benefits. Whether these results pertain to other major depressive disorder patient groups and treatments deserves study.
Authors
- Mark T. Bunker (ORCID: https://orcid.org/0000-0001-5871-0687)
- Harold A. Sackeïm (ORCID: https://orcid.org/0000-0002-1107-4553)
- J.M. Way
- A. John Rush
- Charles R. Conway (ORCID: https://orcid.org/0000-0001-6849-9416)
- Ying-Chieh Lee (ORCID: https://orcid.org/0000-0002-5414-5497)
- Scott T. Aaronson (ORCID: https://orcid.org/0000-0001-7616-8801)
- Roger S. McIntyre (ORCID: https://orcid.org/0000-0003-4733-2523)
- Sheldon Preskorn
- Olivia Shy
- Quyen Tran
- Charles M. Gordon (ORCID: https://orcid.org/0000-0001-7733-9342)
Institutions
- Medical University of South Carolina (US)
- University of Toronto (CA)
- Washington University in St. Louis (US)
- Wichita State University (US)
- Sheppard Pratt Health System (US)
- Duke-NUS Medical School (SG)
- LivaNova (United Kingdom) (GB)
- Wichita Clinic (US)
- Professional Beef Services (US)
Publication Details
- Journal
- Journal of Mood and Anxiety Disorders
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.xjmad.2025.100121
- Citations
- 3
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Massachusetts General Hospital
- University of Pennsylvania
- Ohio State University
- Emory University
- Texas Tech University
- University of Missouri
- University of Minnesota
- Carilion Clinic
- Rush University
- University of South Carolina
- Augusta University
- LivaNova
- Stony Brook University
- University of California, San Diego
- Perelman School of Medicine, University of Pennsylvania