Evaluation of the survival-inferred fragility index to assess the robustness of the estimated treatment effect on survival endpoints

The SIFI should not be used as a measure of robustness of survival trials, as it relates to a very specific group of individuals. At least, a random selection of patients should be used in its calculation.

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Publication Details

Journal
Contemporary Clinical Trials
Published
2025-04-14
DOI
https://doi.org/10.1016/j.cct.2025.107906
Primary Topic
Health Systems, Economic Evaluations, Quality of Life
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of the survival-inferred fragility index to assess the robustness of the estimated treatment effect on survival endpoints

Roland Couturier, Jérôme Lambert, Sylvie Chevret
Contemporary Clinical Trials
Health Systems, Economic Evaluations, Quality of Life
article

Evaluation of the survival-inferred fragility index to assess the robustness of the estimated treatment effect on survival endpoints

Roland Couturier, Jérôme Lambert, Sylvie Chevret
article en

Abstract

The SIFI should not be used as a measure of robustness of survival trials, as it relates to a very specific group of individuals. At least, a random selection of patients should be used in its calculation.

Contemporary Clinical TrialsVol. 153
Inserm (FR), Institut Universitaire de France (FR), Université Paris Cité (FR), Eau de Paris (France) (FR), Centre de Recherche Épidémiologie et Statistique (FR)
Zero hunger
Openalex Percentile: Top 89%
Health Systems, Economic Evaluations, Quality of Life
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