Direct RNA sequencing reveals chicken post-transcriptional modifications in response to Campylobacter jejuni inoculation
This study provided a post-transcriptional modification profile in the chicken cecum post C. jejuni inoculation, including alternative splicing, poly(A) tail length, m<sup>6</sup>A and m<sup>5</sup>C modifications. ENSGALG00000012480 and IFIH1 could be potential candidate genes as epigenetic markers following C. jejuni inoculation. The findings provide new insights into the complexity of expression regulation and data resource of the epitranscriptome, enhancing our understanding on epigenetic modification regulating C. jejuni inoculation.
Authors
- Yuanmei Wang (ORCID: https://orcid.org/0000-0002-5628-2276)
- Yanru Ren (ORCID: https://orcid.org/0000-0003-1345-4020)
- Xianyao Li (ORCID: https://orcid.org/0000-0002-9904-4809)
- Long Liu (ORCID: https://orcid.org/0000-0003-0875-060X)
- Tianyi Wang (ORCID: https://orcid.org/0000-0002-7525-5564)
- Liying Liu
- Yanan Zhao (ORCID: https://orcid.org/0000-0002-9416-8271)
Institutions
- Ministry of Agriculture and Rural Affairs (CN)
- Shandong Agricultural University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1186/s12864-025-11564-3
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Key Research and Development Program of China