Impact of Point-of-care Allogeneic Red Blood Cell Washing on Markers of Transfusion-related Respiratory Complications: A Phase II Randomized Clinical Trial
Among patients undergoing cardiovascular surgery with high risk of erythrocyte transfusion, point-of-care washing of allogeneic erythrocyte transfusions did not mitigate changes in intermediate markers of lung injury or cardiopulmonary physiologic responses to erythrocyte transfusion and was not associated with improved clinical outcomes.
Authors
- Phillip J. Schulte (ORCID: https://orcid.org/0000-0001-6575-4741)
- Laurie Meade
- Matthew A. Warner (ORCID: https://orcid.org/0000-0002-6625-8755)
- Paula J. Santrach
- Mihai V. Podgoreanu (ORCID: https://orcid.org/0000-0001-5539-4674)
- Philip J. Norris (ORCID: https://orcid.org/0000-0003-0526-2088)
- Clara Di Germanio (ORCID: https://orcid.org/0000-0002-6047-211X)
- Chelsea M. Conn
- Richard S. Pendegraft
- Ian J. Welsby (ORCID: https://orcid.org/0000-0002-2789-5612)
- Daryl J. Kor (ORCID: https://orcid.org/0000-0001-9110-1648)
- Erica D. Wittwer (ORCID: https://orcid.org/0000-0001-6088-1661)
- Sarah Armour
Institutions
- Mayo Clinic (US)
- University of California, San Francisco (US)
- WinnMed (US)
- Pacific Research Institute (US)
- Duke Raleigh Hospital (US)
- Mayo Clinic in Arizona (US)
- Duke Medical Center (US)
- Vitalant (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Anesthesiology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1097/aln.0000000000005505
- Citations
- 2
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 1.55